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Sentra PM

Clinical trial result

Comparable

to trazodone on key sleep quality metrics

Double-blind placebo-controlled trial, 111 participants.

What it does

Sentra PM results.

Wake up rested

Targets sleep quality, not just sleep duration. Patients describe deeper, more restorative nights.

Stay asleep through the night

Supports the neurochemical balance that keeps you in deep sleep cycles without waking.

No morning grogginess

Non-sedating mechanism. Wakes you up clear, not foggy.

Non-habit forming

No dependency, no tolerance build-up reported.

The mechanism

Sleep Architecture Restoration

Supports serotonin and melatonin pathways so your nervous system can enter deep, restorative sleep on its own.

Vs traditional approach

How Sentra PM differs

  • Mechanism

    Prescription sleep aids (trazodone, zolpidem): Sedative or hypnotic
    Sentra PM: Neurotransmitter precursor support

  • Next-day grogginess

    Prescription sleep aids (trazodone, zolpidem): Common side effect
    Sentra PM: None reported

  • Dependency

    Prescription sleep aids (trazodone, zolpidem): Tolerance and rebound risk
    Sentra PM: Non-habit forming

  • Head-to-head evidence

    Prescription sleep aids (trazodone, zolpidem): —
    Sentra PM: Published trial vs trazodone
Prescription sleep aids (trazodone, zolpidem)Sentra PM

What's inside

Ingredient spotlight

  • 01

    L-Tryptophan

    Serotonin and melatonin precursor

  • 02

    5-HTP

    Direct serotonin precursor

  • 03

    GABA

    Calming inhibitory neurotransmitter

  • 04

    Choline bitartrate

    Supports healthy nervous system signaling

30–60 day supply depending on dose

How to use it

Your protocol

  1. 1

    30–60 min before bed

    1–2 capsules without food. Consistency matters — take at the same time every night.

  2. 2

    First 2 weeks

    Many patients see measurable improvements in wearable sleep scores within 10–14 days.

  3. 3

    If you wake

    An additional 1–2 capsules mid-night is safe.

Patient outcome

“I had tried trazodone, zolpidem, melatonin gummies. Sentra PM is the first thing that made me wake up feeling like I actually slept.”

Dena Holloway

· age 54

Your guarantee

Practitioner-backed. Medixa-shipped.

Your clinician stays in the loop

Every Sentra PM order is logged to your practitioner's dashboard. Questions route back to them first, not to a chatbot.

Free shipping after the first bottle

Auto-refill shipping is included. Cancel from your patient portal any time.

30-day satisfaction window

Not feeling a change? Your practitioner can swap you to a different formulation within the first 30 days.

Sleep SupportMedical food; physician supervision required

Sentra PM

60 ct

Dietary management of sleep disorders

A nighttime encapsulated medical food intended for people with poor sleep quality, repeated awakenings, or non-restorative sleep. Unlike sleep aids that sedate, Sentra PM works by restoring the deeper nighttime nervous system activity needed for truly restorative sleep.

Key differentiator

Best positioned for restorative sleep support in patients whose sleep is disrupted by chronic illness, pain, or long-term stress

Backed by 2 clinical studies

Suggested retail

$54.95

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Clinical Details

How It Works

Sentra PM supplies amino acid precursors that support nighttime neurotransmitter balance, promoting the physiological conditions for deep, restorative sleep rather than pharmacological sedation.

Dosage

1-2 capsules at bedtime; additional 1-2 during the night if needed; take without food.

Safety

No significant drug interactions reported. Non-sedating mechanism reduces next-day grogginess risk. Ingredients are GRAS.

Evidence Summary

Clinical deck plus formulation sheet plus public page

A double-blind, placebo-controlled, randomized trial of 111 participants showed shorter time to fall asleep in the Sentra PM plus trazodone group and described support for nighttime neurotransmitter balance.

Published Research

Peer-reviewed studies supporting Sentra PM.

Sentra PM (a Medical Food) and Trazodone in the Management of Sleep Disorders

Featured study

Administration of an Amino Acid-Based Regimen for the Management of Autonomic Nervous System Dysfunction Related to Combat-Induced Illness

Also in Sleep Support

GABAdone

GABAdone

Difficulty falling asleep, racing mind, anxiety-related insomnia

$54.95

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