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Theramine

Clinical trial result

50.3%

pain reduction vs baseline

Published double-blind trial. Ibuprofen control group showed +0.73%.

What it does

Theramine results.

Back to baseline

Targets the metabolic pathways chronic pain disrupts, not just the pain signal itself.

Inflammation support

Formulated for chronic low back pain, headaches, and fibromyalgia.

No COX inhibition

Avoids the GI and kidney concerns that come with long-term NSAID use.

Physician-developed

Published clinical research in the management of chronic inflammatory pain.

The mechanism

Amino Acid Precursor Therapy

Supplies the building blocks your body needs to make pain-modulating neurotransmitters, instead of blocking COX enzymes the way NSAIDs do.

Vs traditional approach

How Theramine differs

  • Mechanism

    NSAIDs (ibuprofen, naproxen): COX-1/2 enzyme inhibition
    Theramine: Amino acid precursor therapy

  • GI bleeding risk

    NSAIDs (ibuprofen, naproxen): Elevated with long-term use
    Theramine: No COX inhibition

  • Kidney concern

    NSAIDs (ibuprofen, naproxen): Cumulative risk
    Theramine: No reported concern at labelled dose

  • Pain score in trial

    NSAIDs (ibuprofen, naproxen): +0.73% (ibuprofen)
    Theramine: −50.3%
NSAIDs (ibuprofen, naproxen)Theramine

What's inside

Ingredient spotlight

  • 01

    L-Arginine

    Nitric-oxide precursor for blood flow and inflammatory balance

  • 02

    L-Glutamine

    Supports neurotransmitter synthesis and tissue repair

  • 03

    GABA

    Inhibitory signaling for pain modulation

  • 04

    Choline bitartrate

    Supports healthy nerve signaling

30-day supply at 2 capsules twice daily

How to use it

Your protocol

  1. 1

    Week 1

    Take 2 capsules twice daily without food. Many patients notice the first change in pain scores inside the first 14 days.

  2. 2

    Week 4

    Published trial showed statistically significant pain reduction by day 28.

  3. 3

    Ongoing

    Safe for long-term use. No reported significant drug interactions across 30M+ doses.

Patient outcome

“Six weeks on Theramine and my back pain scores went from a constant 7 to a 3 on a bad day. I stopped reaching for ibuprofen every morning.”

Marcelo Ruiz

· age 58

Your guarantee

Practitioner-backed. Medixa-shipped.

Your clinician stays in the loop

Every Theramine order is logged to your practitioner's dashboard. Questions route back to them first, not to a chatbot.

Free shipping after the first bottle

Auto-refill shipping is included. Cancel from your patient portal any time.

30-day satisfaction window

Not feeling a change? Your practitioner can swap you to a different formulation within the first 30 days.

Pain ManagementMedical food; physician supervision required

Theramine

120 ct

Dietary management of pain syndromes and inflammatory conditions

A physician-developed encapsulated medical food intended for people living with chronic pain or inflammation, including low back pain, headaches, or fibromyalgia. Theramine targets the metabolic root of pain through amino acid precursor therapy rather than masking symptoms.

Key differentiator

Best positioned for general chronic pain and inflammation rather than nerve-specific or joint-specific pain

Backed by 3 clinical studies

Suggested retail

$54.95

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Clinical Details

How It Works

Theramine supplies amino acid precursors that support neurotransmitter synthesis involved in pain modulation and inflammatory response regulation. The formulation targets the metabolic pathways disrupted in chronic pain conditions.

Dosage

2 capsules twice daily; take without food or as directed by physician.

Safety

No significant drug interactions reported. Over 30 million doses safely dispensed. Ingredients are GRAS (Generally Recognized As Safe).

Evidence Summary

Clinical deck plus formulation sheet plus public page

A 28-day double-blind, randomized, multicenter trial of 127 subjects with chronic established back pain showed Theramine achieved statistically significant pain reduction versus naproxen and ibuprofen, with inflammatory marker improvements also reported.

Published Research

Peer-reviewed studies supporting Theramine.

A Double-Blind Controlled Trial of a Single Dose Naproxen and an Amino Acid Medical Food Theramine for the Treatment of Low Back Pain

Featured study

Reduction in Pain and Inflammation Associated With Chronic Low Back Pain With the Use of the Medical Food Theramine

Theramine (A Medical Food) Versus Non-Steroidal Anti Inflammatory Agents in Elderly Patients: A Pharmacoeconomic Analysis

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